【AKI】To predict AKI outbreak after cardio-vascular surgery
Comparison between different biomarkers after cardio-vascular surgery
*P<0.05, compared with the non-AKI group at the same timepoint
+P<0.05 compared with the respective preoperative level in the same group
Figure from Matsui, K. et al., Circulation Journal. 76(1), 2012 
The level of serum creatinine, urinary L-FABP, NGAL and NAG before and after surgery of 85 patients who underwent cardiovascular surgery, were deducted. This population was divided according to AKIN criteria into 2 groups with or without AKI development and above parameters were examined.
Urinary L-FABP level just right after surgery and 3 hours after intervention in AKI group, has significantly increased comparing its level before the surgery. Also the comparison of L-FABP level between AKI and non AKI groups shows that its level is significantly high in AKI group. This results shows that urinary L-FABP is able to determine risk of developing AKI in early stage.
 Matsui, K. et al., Usefulness of urinary biomarkers in early detection of acute kidney injury after cardiac surgery in adults. Circulation Journal. 76(1), 2012. J-STAGE