L-FABP is a kind of "fatty acid binding proteins" with a molecular weight of 14kDa located in the cytoplasm of human renal proximal tubular cells.
L-FABPs are excreted in urine due to:
- ischemia (or low capillary blood flow) and
- oxidative stress on renal tubule
before progression of tissue damage
Useful for early diagnosis of
renal disease accompanying tubular dysfunction